What is cord blood?
Cord blood is the blood that remains in a baby’s umbilical cord and placenta immediately after the baby is born and the umbilical cord has been clamped and cut.
Cord blood is rich in blood stem cells, in particular haematopoietic stem cells (HSCs), and other important cells that have the ability to create and heal our organs, blood, tissue and the immune system. These cells from the umbilical cord are in pristine condition making them some of the most flexible and potent in the body.
Are cord blood stem cells different from other stem cells?
Yes, cord blood stem cells differ from other types of adult stem cells. Cord blood has the following benefits:
Simple and non-invasive:
- Cord blood is easily collected is painless for both mother and baby
- Minimal waiting time between need and time of treatment There is no need to locate a compatible donor
- No invasive procedure to harvest bone marrow if required
Cord blood medical advantages:
- Cord blood stem cells are more potent than adult stem cells
- Environmental pollutants, viruses and chemicals have not yet affected the cord blood stem cells
Cord blood flexibility:
- Decreased potential for graft vs host disease and lower incidence of viral transmissions
A perfect match:
- Your baby's umbilical cord stem cells are an exact match for your child.
- The closer the match, the better chance of the body accepting the cells
Why store your baby's cord blood?
Cord blood and cord tissue are rich in powerful stem cells and can only be collected at birth for potential future use.
Stem cells are being used today for medical treatments, and there is an increasing range of new therapies being investigated that anticipate using cord blood and tissue in the future. Your baby's stem cells are a perfect match for your child.
Who can use your baby’s cord blood?
The cord blood and tissue cells are owned by you and your child and can only be released for use for your child.
Should I store cord blood and tissue for each child?
By banking cord blood and tissue for every child, you are making sure that they will have access to their own cells if they ever needed. This is particularly important as more regenerative medicine applications become available.
Why store cord tissue as well as cord blood?
Both products have different types of cells, which have the potential for different types of treatment. Cord blood is a rich source of (haemopoietic stem cells or HSCs) and other types of immune cells. Cord tissue contains mesenchymal stem cells (MSCs), which form into bone, cartilage, muscle and tendon. MSCs have qualities that dampen the immune system and reduce inflammation. These two cell groups (HSCs and MSCs) have different roles in the body, therefore lead to the potential for different treatments.
How is cord blood and tissue collected?
Cord blood and tissue is collected by a trained obstetrician or midwife.
The collection happens immediately after your baby is born and the cord has been clamped and cut. The cord blood is collected into a sterile collection bag. The procedure is painless for both mother and baby, and takes around three minutes. The cord tissue is collected after the placenta has been delivered. Find out how it works here.
When should the cord be clamped?
An important requirement for cord blood collection is the timing of the clamping and cutting of the umbilical cord. Generally a baby’s cord is clamped within one minute of birth. This time frame ensures the cord blood remains in the umbilical cord and placenta for collection. Research has shown that the volume of cord blood collected at birth is directly related to the success of the cord blood transplant - the greater the cord blood volume, the better the clinical outcome of the treatment.
Delayed cord clamping and cord blood banking can both be achieved through consultation with your health care professional and Cell Care. Health care providers can manage both reasonable delayed cord clamping and cord blood collections. If delayed cord clamping is part of your birth plan, we recommend a delay of up to 60 seconds to ensure we still achieve our average collection volume – remembering that the amount of cord blood collected relates closely to the cell dose that may be obtained from any given collection. In the first minute after birth, up to 80% of blood volume is transferred from the placenta to the baby. This means that 1 minute of delayed cord clamping allows for your baby to receive the majority of cord blood at birth and still achieve sufficient cord blood for long term banking.
How much blood needs to be collected?
Evidence shows that the more stem cells collected means more cells are transplanted. This increases the survival rate of the cells during transplant. The number of stem cells available depends on the amount of cord blood collected.
What happens if a low volume of cord blood is collected?
Cell Care analyses the number of stem cells in every cord blood sample. Occasionally there will be less stem cells than expected. In this case, if the cell count exceeds our minimum benchmark you will be given the option to decide whether you wish to continue storage of the sample.
Does it matter which type of birth I have?
Cord blood and tissue collection is not affected by your method of delivery. The collection takes place once your baby is born and the umbilical cord has been cut and clamped.
If you are having a caesarean delivery, our collection pack is entirely sterile and suitable for use in theatre.
What happens if my baby is born prematurely?
Premature birth is not an issue unless your baby is born at earlier than 34 weeks gestation. Deliveries earlier than this generally result in a smaller baby and therefore a smaller placenta, and this normally does not allow for a adequate collection of cord blood. Cell Care may collect prior to 34 weeks gestation, following written approval from your healthcare provider.
What about contamination?
Cell Care's standard procedure is to continue storage of cord blood if a bacterial contamination is contracted. Contamination of stem cell products (either cord blood, bone marrow or peripheral blood) is not a contraindication to storage, and samples can be used for transplantation together with antibiotics. If the sample be needed for use, the treating physician will be informed of the contamination, and the antibiotic sensitivities of the organism. This process is in line with FACT/Netcord Standard's.
Does the hospital need anything to do the collection?
No. Once you register with Cell Care you will receive a collection pack containing everything that your lead maternity carer, obstetrician or midwife will need to collect your baby's cord blood and tissue. You just need to remember to take the pack with you to the birth centre when you go in to have your baby.
Hospital staff do not perform the cord blood and tissue collection. If your LMC is part of the hospital team, please let us know.
Can you collect from rural parts of the country?
Cell Care transports from most regional birthing centres. This can usually be achieved in less than 24 hours.
Further, the Cell Care transport container and its temperature stabilising elements have been specifically designed to maintain optimal conditions during transport.
How will I know that my baby's cord blood and tissue stem cells have been received?
When your baby's cord blood and tissue has arrived at our facility, you will receive a confirmation text message. Cell Care's scientists process your baby's stem cells as soon as the cord blood and tissue samples arrive at our facility. Our processing facility operates 365 days a year.
You will also receive a follow up call to confirm the storage status of your cord blood and tissue within two weeks of your baby's birth.
How do I know that my baby’s cord blood and tissue will not be mixed up with someone else’s?
Cell Care ensures that your sample cannot be mixed up at any point using a triple-identification system:
- Your collection kit is allocated a unique barcode that is used at every step of the collection
- The barcode labels have been validated for use on all elements of the collection kit including the collection bag, freezing bags, paperwork and all critical applications during processing and storage
- All of the components used for processing and storage are individually identified and allocated for your specific use
- The birth mother’s name is permanently attached to each step of the collection, processing and storage process
- The cassette barcode label and storage location for your baby's cord blood and tissue is kept in our validated computer system, which is backed up every day
What tests are carried out on the cord blood?
Your baby's cord blood is tested for:
- Bacterial contamination
- Total Cell Number
- Cellular Viability
Stem cells are difficult to identify just by looking at them; the only proof that a cell is a stem cell is determined by how it acts when it multiplies. Therefore Scientists have developed a number of tests to determine the amount of stem cells in a sample. A protein found on the surface of stem cells is called CD34+ and this is the best known marker for blood-forming cells. Cell Care conducts these tests using its own state-of-the-art instrument (called a flow cytometer).
We also store frozen vials of cord blood plasma and buffy coat cells. These can later be used for extra testing, for example prior to release of the sample for use.
What tests are carried out on the maternal blood?
Every cord blood sample is accompanied by a maternal blood sample. This is taken at the time of baby’s birth, usually before your baby is delivered. This is tested for some of the following infectious agents;
- HIV
- Hepatitis B and C
- HTLV
- Syphilis
We understand that these tests have often been carried out during pregnancy however it is important for them to be done at the time of delivery, as the results can inform us if the cord blood is infected with any of the above pathogens.
Where is my baby’s cord blood and tissue stored?
Cell Care has its own state-of-the-art processing and storage facility in Melbourne, Australia. The facility has controlled swipe card access, constant CCTV security monitoring, and back-to-base intrusion alarms monitored by an external security company 365 days a year. Critical areas have been temperature-mapped and are continuously monitored. Each cryogenic storage vessel is supplied with liquid nitrogen from a 12,000L bulk liquid nitrogen tank. This is via vacuum insulated piping that ensures the cells have a continuous source of liquid nitrogen.
How are the cord blood and tissue stem cells stored?
Once the cells have been through the processing phase, they are transferred to a cryogenic storage tank for long-term storage in the vapour phase of liquid nitrogen.
How long can the stem cells be stored for?
Scientists have determined that all cell activity stops once the cells are frozen and stored at cryogenic temperatures. There is no potential for further damage because there is no molecular movement meaning the cells can be stored for extended amounts of time without compromising their integrity.
Currently cord blood stem cells do not have a use-by date. Published research suggests that there is no cell degeneration after 30 years of cryopreservation. Comparatively, bone marrow and other human tissues and cells have been stored for decades and have stayed viable. There is no reason to believe that the same would not be true for cord blood and tissue stem cells.
How do I access my baby’s stem cells if ever needed?
If you do need to use your cord blood and tissue cells for a medical treatment or a clinical trial, please contact Cell Care. There are TGA approval requirements that need to be met prior to the cells being released and we will assist you in meeting these.
Importantly, there is no charge for the release or transportation of the samples if they are ever required.
Has Cell Care released any cells for use?
The cord blood units that Cell Care has released have been used for therapeutic use in both a clinical and approved research setting. All of our releases to date have been viable for use – this is the ultimate validation of our quality processing and storage technique.
What is the likelihood of ever using banked cord blood?
It is difficult to predict the probability of using stored cord blood. There are many factors that impact the likelihood of use including:
- the prevalence of disease
- treatment options available
- age
- therapies that may be approved in the future
It is important to note that estimates of use may differ significantly for these reasons. Today, based on currently approved therapies and ignoring the trials and research being undertaken, the chance of a child needing a stem cell therapy is 1 in 3,000 2.
Over a person’s lifetime the likelihood of requiring stem cell therapy is estimated at 1 in 2002.
How do I enrol with Cell Care?
Cell Care offers a complete online enrolment. It's a simple 4-step process that takes 10 minutes to complete:
1. Choose whether to bank cord blood, or cord blood and tissue
2. Select your payment plan
3. Pay a deposit of $145
4. Complete medical questionnaire
If I answer "yes" on my medical questionnaire does this mean my baby's cord blood and tissue cannot be collected and stored?
A 'Yes' response to any question on the medical questionnaire does not necessarily mean your baby's cord blood and tissue are not able to be stored. The medical questionnaire is designed to alert us to potential medical conditions, which may affect the condition or viability of your cord blood and tissue sample. The medical questionnaire also provides important medical information for a doctor to consider, prior to using your baby's cord blood and tissue for transplantation.
If you have answered yes to any of the critical questions the laboratory may request that you send a copy of your serology test results that were taken by your obstetrician or health care provider during your pregnancy. This is to minimise the risk to both couriers and laboratory staff handling contaminated blood.
Cord blood that is positive for HIV or hepatitis C cannot currently be banked with Cell Care. If you answer yes to any other questions Client Services will discuss them with you when you enrol with us.
When should I enrol?
To be absolutely certain to receive your collection kit before going to give birth, we suggest enrolling as early as possible. We send your collection kit to you when you are 34 weeks pregnant. Cell Care will do everything possible to facilitate last minute registrations.
I am having my baby in a public hospital. Can I still store the cord blood and tissue privately?
Yes, Cell Care has an extensive network of trained collectors who can facilitate collections from public and private hospitals around Australia. Our collectors can provide this service 24 hours a day, 7 days a week, 365 days a year (public holidays included).
How much does it cost?
Cell Care offers clear and flexible pricing options, use our pricing options to see and compare our different pricing plans.
Annual or prepaid, what storage option is right for me?
With Annual Storage Plans, you pay a processing fee for the collection kit, transport, processing and testing of the cord blood and tissue collected. This fee comprises of a deposit paid at enrolment, with the balance payable in a lump sum two weeks after birth or over a 12 month payment schedule. An annual storage fee is then paid for as long as you wish to continue storing and without fixed time commitment. The annual fee, adjusted for CPI (*further subject to change), covers one year of cryogenic storage. The first payment is payable three months after birth, and thereafter payable annually.
Annual Storage Plans are ideal for those who wish to minimise their initial financial commitment. Annual Storage plans may be switched to a Prepaid Storage Plan at a later stage if requested.
Prepaid Storage Plans combine fees associated with the collection kit, transport, processing, testing and storage of the cord blood and tissue for 20 or 30 years of storage, or our new Lifetime storage plans#.
With a Prepaid Storage plan, there is a deposit payable at enrolment with the balance payable either in a lump sum two weeks after birth or by either a 12 or 24 monthly payment schedule. Payments start from $215 per month for a 24 month period for 20 years of cord blood storage.
To view the current Cell Care banking and client agreement, please click on the link below:
Cell Care Client Agreement (905 KB)
#Lifetime is defined as an average of 83 years for males & females (Australian Bureau of statistics for life expectancy 2020-2022)
Are there discounts for previous clients or multiple births?
Yes, Cell Care has special pricing options for multiple births and siblings.
Existing client, you are entitled to:
- $200 reduction applies for each baby when you are storing cord blood, or
- $400 reduction if you choose to store cord blood and tissue
If you're having twins:
- $200 reduction applies for each baby if you are storing cord blood
- $400 reduction applies for each baby if you are storing cord blood and tissue
If you are having triplets, please call Cell Care on 0800 088 235 so that special arrangements may be made for you.
What is Cell Care’s refund policy?
Pregnancy and birth can be an unpredictable process and this may impact the volume of cord blood collected or the ability to collect cord blood and tissue at all.
While it happens infrequently, if we are unable to collect and store your baby’s cord blood or tissue, refunds will be assessed as follows:
Collection and Storage
In the event:
- cord blood and tissue cannot be collected or stored Cell Care will refund all monies paid
- you order cord blood + tissue and one of these products cannot be collected at birth, your payment plan will revert to either a cord blood only plan or cord tissue only plan
Cancellations
If you elect to cancel this contract prior to the birth of your baby and:
- your collection kit has not been dispatched, your deposit will be refunded in full; or
- your collection kit has been dispatched, your deposit will be retained in full; or
- your deposit is non-refundable under the terms and conditions of a specific promotional offer you enrolled under, your deposit will be retained in full.